Agarwal R P, Handler S D, Matthews M R, Carpentieri D
Division of Pediatric Otolaryngology and Department of Pathology, The Children's Hospital of Philadelphia, PA 19104, USA.
Otolaryngol Head Neck Surg. 2001 Nov;125(5):510-5. doi: 10.1067/mhn.2001.117371.
Pilomatrixomas are benign skin neoplasms of hair follicle origin. They are one of the most common superficial masses of the head and neck excised in children. Although the entity has been well studied in the literature, few studies have been undertaken to evaluate the clinical characteristics of head and neck pilomatrixomas specifically in children. The purpose of this study was to review the clinical characteristics and management of children presenting with pilomatrixomas of the head and neck at a large tertiary care pediatric hospital.
A retrospective chart review was performed of all patients with histologically confirmed pilomatrixoma of the head and neck excised during a 6-year period (1992-1997) at the Children's Hospital of Philadelphia.
Ninety-one cases of pilomatrixoma were confirmed in 86 patients. The age range was 5 months to 17 years. The median age at time of excision was 6.0 years. The most common sites of occurrence were the cheek (36%), neck (20%), periorbital region (14%), and scalp (9%). The male to female ratio was 1:1.5. Multiple lesions were found in 8.2% of patients. Surgical excision was curative in all cases.
Pilomatrixoma is a cutaneous neoplasm that is one of most common causes of superficial head and neck masses in children. Although the presurgical diagnosis may be difficult in some cases, pilomatrixoma must be kept in the differential of superficial head and neck masses in children. Surgical excision is almost always curative.
毛发上皮瘤是起源于毛囊的良性皮肤肿瘤。它们是儿童头颈部切除的最常见浅表肿物之一。尽管该实体在文献中已有充分研究,但很少有研究专门评估儿童头颈部毛发上皮瘤的临床特征。本研究的目的是回顾一家大型三级儿科医院中头颈部患有毛发上皮瘤的儿童的临床特征及治疗情况。
对费城儿童医院在1992年至1997年6年间切除的所有经组织学确诊为头颈部毛发上皮瘤的患者进行回顾性病历审查。
86例患者确诊91例毛发上皮瘤。年龄范围为5个月至17岁。切除时的中位年龄为6.0岁。最常见的发病部位是脸颊(36%)、颈部(20%)、眶周区域(14%)和头皮(9%)。男女比例为1:1.5。8.2%的患者发现有多个病灶。所有病例手术切除均治愈。
毛发上皮瘤是一种皮肤肿瘤,是儿童头颈部浅表肿物最常见的病因之一。尽管在某些情况下术前诊断可能困难,但在儿童头颈部浅表肿物的鉴别诊断中必须考虑毛发上皮瘤。手术切除几乎总是能治愈。