科迈德K4b2便携式呼吸气体分析系统与代谢车在测量FEO2、FECO2和VE方面的准确性和一致性水平。
The level of accuracy and agreement in measures of FEO2, FECO2 and VE between the Cosmed K4b2 portable, respiratory gas analysis system and a metabolic cart.
作者信息
Pinnington H C, Wong P, Tay J, Green D, Dawson B
机构信息
Department of Human Movement and Exercise Science, The University of Western Australia.
出版信息
J Sci Med Sport. 2001 Sep;4(3):324-35. doi: 10.1016/s1440-2440(01)80041-4.
This study aimed to assess the accuracy of the Cosmed K4b2 (Cosmed, Italy) portable metabolic system that measures FEO2, FECO2 and VE on a breath by breath basis. For gas concentration comparisons, expired air from 20 subjects performing treadmill running was collected in a 600 litre chain compensated Collins Tissot tank and analysed for FEO2 and FECO2 using a laboratory metabolic cart and the Cosmed K4 b2 metabolic system. For ventilation comparisons, serial steady state VE (STPD) values were measured on 10 subjects using the Cosmed K4b2 ventilation turbine and a Morgan ventilation monitor during a continuous treadmill running protocol at ascending speeds of 8, 11 and 14 km x h(-1). The Cosmed K4b2 FEO2 and FECO2 measures were significantly lower (P < 0.001) than the metabolic cart values. Pearson correlation coefficients (r) and the standard error of measurement (SEM) demonstrated a high association between the Cosmed and the metabolic cart measures (FEO2 r =0 .971, SEM 0.071: FECO2 r = 0.925, SEM 0.087). Cosmed VE (l x min(-1)) measures were significantly greater than Morgan values at running speeds of 8 kmh(-1) (P < 0.001) and 11 kmh(-1) (P < 0.001) but not significantly different at 14 km x h(-1) (P > 0.05). When VE measures at the three running speeds were combined, the mean difference between instrument measures ranged between 3.5 - 4.0 l x min(-1) but the values were highly correlated (r= 0.982, P<0.01; SEM 3.03). Linear regression analysis revealed the following regression equations to predict metabolic cart values from Cosmed measures: FEO2 = 0.852+0.963 Cosmed (R2 = 0.940, P<0.00 1), FECO2 = 0.627+0.878 Cosmed (R2=0.856, P<0.001), VE = -2.50+0.984 Cosmed (R2 = 0.965. P < 0.001). The results indicated that the Cosmed K4b2 unit assessed here produced measures of FEO2, FECO2 and VE that had strong correlation to values obtained from a metabolic cart. However, linear regression analysis may further improve the accuracy of Cosmed K4b2 measures when compared to metabolic cart values.
本研究旨在评估意大利科美（Cosmed）公司生产的K4b2便携式代谢系统在逐次呼吸基础上测量呼气末氧分数（FEO2）、呼气末二氧化碳分数（FECO2）和每分钟静息通气量（VE）的准确性。为了进行气体浓度比较，将20名进行跑步机跑步的受试者呼出的气体收集到一个600升的链式补偿柯林斯·蒂索特（Collins Tissot）气罐中，并使用实验室代谢车和科美K4b2代谢系统分析FEO2和FECO2。为了进行通气比较，在10名受试者进行连续跑步机跑步试验时，以8、11和14 km·h⁻¹的递增速度，使用科美K4b2通气涡轮机和摩根通气监测仪测量系列稳态VE（标准温度和压力干燥状态下）值。科美K4b2测量的FEO2和FECO2显著低于代谢车测量值（P < 0.001）。皮尔逊相关系数（r）和测量标准误差（SEM）表明科美测量值与代谢车测量值之间具有高度相关性（FEO2：r = 0.971，SEM 0.071；FECO2：r = 0.925，SEM 0.087）。在8 km·h⁻¹（P < 0.001）和11 km·h⁻¹（P < 0.001）的跑步速度下，科美测量的VE（升·分钟⁻¹）显著高于摩根测量值，但在14 km·h⁻¹时无显著差异（P > 0.05）。当将三种跑步速度下的VE测量值合并时，仪器测量值之间的平均差异在3.5 - 4.0升·分钟⁻¹之间，但这些值具有高度相关性（r = 0.982，P < 0.01；SEM 3.03）。线性回归分析得出以下回归方程，用于根据科美测量值预测代谢车测量值：FEO2 = 0.852 + 0.963×科美测量值（R² = 0.940，P < 0.001），FECO2 = 0.627 + 0.878×科美测量值（R² = 0.856，P < 0.001），VE = -2.50 + 0.984×科美测量值（R² = 0.965，P < 0.001）。结果表明，此处评估的科美K4b2设备测量的FEO2、FECO2和VE与代谢车获得的值具有很强的相关性。然而，与代谢车测量值相比，线性回归分析可能会进一步提高科美K4b2测量的准确性。
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