Vanderhoof J A, Young R J
Department of Pediatrics, University of Nebraska Medical Center, Omaha, Nebraska 68198-5160, USA.
Curr Opin Clin Nutr Metab Care. 2001 Nov;4(6):553-6. doi: 10.1097/00075197-200111000-00016.
Allergic disorders of the gastrointestinal tract were once thought of as primarily dermatological manifestations of common food allergens such as peanuts. Recently, greater attention to these products has arisen as complex mechanisms of action have been more clearly delineated. Specific disease states have recently been recognized associated with gastrointestinal reactions to foods, such as celiac disease, infantile formula protein intolerance, and eosinophilic gastroenteritis have been well described. More recently, eosinophilic esophagitis and allergic constipation have been described. This article will review current information regarding the commonly identified gastrointestinal allergic states, and more detailed information regarding two new allergic entities will also be described.
胃肠道过敏性疾病曾被认为主要是常见食物过敏原(如花生)的皮肤表现。最近,随着复杂的作用机制得到更清晰的描述,人们对这些疾病给予了更多关注。最近已认识到一些特定疾病状态与食物引起的胃肠道反应有关,如乳糜泻、婴儿配方奶粉蛋白不耐受,嗜酸性粒细胞性胃肠炎也有了详细描述。最近,又有嗜酸性粒细胞性食管炎和过敏性便秘的报道。本文将综述目前有关常见胃肠道过敏状态的信息,并对两种新的过敏疾病实体进行更详细的描述。