Qureshi M I, Qureshi Z
Department of Anatomy, Ayub Medical College, Abbottabad.
J Ayub Med Coll Abbottabad. 2001 Jan-Mar;13(1):8-10.
Protein Malnutrition is one of the major mortality factors in the children of Pakistan. Not only do the children suffer from infections (because of low resistance secondary to malnutrition), but they also lose weight significantly. The two spectra of the diseases are Kwashiorkor and Marasmus. We conducted this study on laboratory animals to assess the weight change and correlated it with the extent of malnutrition by studying and estimating the serum albumin levels as well.
40 male albino rats of 2 weeks age were used for the experiment. They were divided into Control and Experimental groups containing equal number of animals. The experimental group was subjected to protein malnutrition for 3 to 6 weeks. They were killed with the paired control animals. The parameters of the two groups were compared for statistical analysis.
The results showed significant change in the weights of the experimental animals right from the first week of malnutrition while the change in serum albumin level became significant after prolonged malnutrition.
Protein malnutrition is reflected from the decrease in the serum albumin levels of the animals and their weights are also decreased significantly.
蛋白质营养不良是巴基斯坦儿童主要的死亡因素之一。儿童不仅因营养不良导致抵抗力低下而遭受感染，体重也会显著下降。这两种疾病谱分别是夸希奥科病和消瘦症。我们在实验动物身上进行了这项研究，通过研究和估计血清白蛋白水平来评估体重变化，并将其与营养不良程度相关联。
选用40只2周龄的雄性白化大鼠进行实验。将它们分为对照组和实验组，两组动物数量相等。实验组大鼠接受3至6周的蛋白质营养不良处理。之后将它们与配对的对照动物一同处死。对两组的参数进行比较以进行统计分析。
结果显示，从营养不良的第一周起，实验动物的体重就出现了显著变化，而血清白蛋白水平在长期营养不良后才出现显著变化。
蛋白质营养不良可通过动物血清白蛋白水平的降低反映出来，并且它们的体重也会显著下降。
