闭经-溢乳综合征中雌激素反馈异常。
An abnormality of oestrogen feedback in amenorrhoea-galactorrhoea.
作者信息
Glass M R, Shaw R W, Butt W R, Edwards R L, London D R
出版信息
Br Med J. 1975 Aug 2;3(5978):274-5. doi: 10.1136/bmj.3.5978.274.
Abstract
Fourteen patients with amenorrhoea and hyperprolactin-anemia but no evidence of pituitary tumours were each given an intramuscular injection of 1 mg oestradiol benzoate. Thirteen patients failed to release luteinizing hormone in response to the oestrogen. This hypothalamic abnormality may help to explain the menstrual disturbances in subjects with hyperprolactinaemia.
摘要
十四名患有闭经和高催乳素血症性贫血但无垂体肿瘤证据的患者，每人接受了1毫克苯甲酸雌二醇的肌肉注射。十三名患者对雌激素无促黄体生成素释放反应。这种下丘脑异常可能有助于解释高催乳素血症患者的月经紊乱。
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