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新生期胸腺切除对大鼠血浆及各组织中镁含量的影响。

Effect of neonatal thymectomy on the content of magnesium in the plasma and in various tissues of the rat.

作者信息

Deschaux P, Massengo B, Charnot Y, Fontanges R

出版信息

Can J Physiol Pharmacol. 1975 Jun;53(3):501-3.

PMID:1170928
Abstract

White rats were thymectomized neonatally. After 60 days, no alteration was noted in the plasma or testis magnesium level. On the other hand, a marked decrease was observed in the magnesium content of muscle (-23%) and of bone (-19%). The injection of thymosin reversed these changes. These findings suggest that a correlation between the thymus and the muscle is exerted by a protein factor (thymosin), and that the thymus may act on sex glands through an indirect pathway.

摘要

新生小白鼠进行了胸腺切除手术。60天后,血浆或睾丸中的镁水平未发现变化。另一方面,肌肉(-23%)和骨骼(-19%)中的镁含量显著下降。注射胸腺素可逆转这些变化。这些发现表明,胸腺与肌肉之间的关联是由一种蛋白质因子(胸腺素)发挥作用的,并且胸腺可能通过间接途径作用于性腺。

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