ABT-773和阿莫西林-克拉维酸对肺炎链球菌和流感嗜血杆菌的抗生素后效应
Postantibiotic effects of ABT-773 and amoxicillin-clavulanate against Streptococcus pneumoniae and Haemophilus influenzae.
作者信息
Neuhauser M M, Prause J L, Danziger L H, Pendland S L
机构信息
The University of Houston College of Pharmacy, Department of Clinical Sciences and Administration, Houston, Texas, USA.
出版信息
Antimicrob Agents Chemother. 2001 Dec;45(12):3613-5. doi: 10.1128/AAC.45.12.3613-3615.2001.
Abstract
This study determined the postantibiotic effect (PAE) of ABT-773 versus that of amoxicillin-clavulanate against clinical isolates of Streptococcus pneumoniae and Haemophilus influenzae. The PAEs of ABT-773 and amoxicillin-clavulanate ranged from 2.3 to 6.0 h and 0 to 2.2 h against S. pneumoniae and from 2.7 to 9.1 h and 0 to 0.8 h against H. influenzae, respectively.
摘要
本研究测定了ABT - 773与阿莫西林 - 克拉维酸对肺炎链球菌和流感嗜血杆菌临床分离株的抗生素后效应（PAE）。ABT - 773和阿莫西林 - 克拉维酸对肺炎链球菌的PAE分别为2.3至6.0小时和0至2.2小时，对流感嗜血杆菌的PAE分别为2.7至9.1小时和0至0.8小时。
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