Demichelis F, Barbareschi M, Boi S, Clemente C, Dalla Palma P, Eccher C, Forti S
Istituto Trentino di Cultura, Istituto per la Ricerca Scientifica e Tecnologica, Trento, Italy.
Am J Clin Pathol. 2001 Nov;116(5):744-52. doi: 10.1309/D71Y-7RLE-JGJP-A427.
The aim of the present study was to assess whether a telemicroscopy system based on static imaging could provide a remote intraoperative frozen section service. Three pathologists evaluated 70 consecutive frozen section cases (for a total of 210 diagnoses) using a static telemicroscopy system (STeMiSy) and light microscopy (LM). STeMiSy uses a robotic microscope, enabling full remote control by consultant pathologists in a near real-time manner. Clinically important concordance between STeMiSy and LM was 98.6% (95.2% overall concordance), indicating very good agreement. The rates of deferred diagnoses given by STeMiSy and LM were comparable (11.0% and 9.5%, respectively). Compared with the consensus diagnosis, the diagnostic accuracy of STeMiSy and LM was 95.2% and 96.2%. The mean viewing time per slide was 3.6 minutes, and the overall time to make a diagnosis by STeMiSy was 6.2 minutes, conforming to intraoperative practice requirements. Our study demonstrates that a static imaging active telepathology system is comparable to dynamic telepathology systems and can provide a routine frozen section service.
本研究的目的是评估基于静态成像的远程显微镜系统是否能够提供远程术中冰冻切片服务。三名病理学家使用静态远程显微镜系统（STeMiSy）和光学显微镜（LM）对70例连续的冰冻切片病例（共计210次诊断）进行了评估。STeMiSy使用机器人显微镜，使病理会诊医师能够以近乎实时的方式进行完全远程控制。STeMiSy与LM之间具有临床意义的一致性为98.6%（总体一致性为95.2%），表明一致性非常好。STeMiSy和LM给出的延迟诊断率相当（分别为11.0%和9.5%）。与共识诊断相比，STeMiSy和LM的诊断准确率分别为95.2%和96.2%。每张玻片的平均观察时间为3.6分钟，STeMiSy做出诊断的总时间为6.2分钟，符合术中实际要求。我们的研究表明，静态成像主动远程病理系统与动态远程病理系统相当，并且能够提供常规冰冻切片服务。
