Kaiser U, Barth N
Klinik für Hämatologie/Onkologie und Immunologie, Philipps-Universität Marburg, Deutschland.
Acta Haematol. 2001;106(3):133-5. doi: 10.1159/000046604.
We report on a 17-year-old female patient with severe anorexia nervosa (AN) (body mass index of 9.8 kg/m(2)) who developed hypophosphataemia (serum phosphate 0.4 nmol/l) and subsequent haemolytic anaemia during oral refeeding. Hypophosphataemia due to an increased phosphate uptake may lead to a reduction of erythrocyte adenosine triphosphate. This mechanism is important for the differential diagnosis of haemolytic anaemia in patients with AN. To prevent this complication, phosphate supplementation should be considered in the refeeding of severely malnourished patients.
我们报告了一名17岁患有严重神经性厌食症(AN)(体重指数为9.8kg/m²)的女性患者,其在口服重新喂养期间出现了低磷血症(血清磷酸盐0.4nmol/L)及随后的溶血性贫血。由于磷酸盐摄取增加导致的低磷血症可能会导致红细胞三磷酸腺苷减少。这一机制对于AN患者溶血性贫血的鉴别诊断很重要。为预防这一并发症,在对严重营养不良患者进行重新喂养时应考虑补充磷酸盐。