Maldonado J E, Gilchrist G S, Brigden L P, Bowie E J
Mayo Clin Proc. 1975 Jul;50(7):402-6.
The platelets of a patient with the Bernard-Soulier syndrome were studied by electron microscopy. The main abnormalities were the presence of giant and often round platelets, hypertrophic and frequently widely dilated open canalicular system, disorganized microtubules, and platelets with sparse or absent granulation. Although well defined, these ultrastructural morphologic aberrations are not considered diagnostic or pathognomonic of the syndrome.
通过电子显微镜对一名患有伯纳德-苏利耶综合征患者的血小板进行了研究。主要异常表现为存在巨大且通常呈圆形的血小板、肥大且常常广泛扩张的开放管道系统、微管排列紊乱以及颗粒稀少或缺乏的血小板。尽管这些超微结构形态学异常特征明确，但并不被认为是该综合征的诊断性或特征性表现。
