Manganaro R, Mamì C, Marrone T, Marseglia L, Gemelli M
Neonatology Unit of the University of Messina, 98100 Messina, Italy.
J Pediatr. 2001 Nov;139(5):673-5. doi: 10.1067/mpd.2001.118880.
To verify in exclusively breast-fed, term infants the incidence of hypernatremic dehydration and identify possible maternal and/or infant factors that interfere with successful breast-feeding.
We prospectively included all healthy breast-fed neonates referred to our Neonatology Unit between October 1999 and March 2000. All neonates with a weight loss > or = 10% of birth weight had a breast-feeding test and a determination of serum sodium, urea, and base excess. Student t test and chi-square test were used for statistical analysis of the data.
Of 686 neonates, 53 (7.7%) had a weight loss > or = 10% of the birth weight, and 19 also had hypernatremia. These 53 neonates had a significantly higher incidence of caesarean delivery and lower maternal education than neonates with a weight loss < 10%.
Our prospective study demonstrates that a weight loss > or = 10% during the first days of life is frequent. Daily weight evaluation, careful breast-feeding assessment, and early routine postpartum follow-up are effective methods to prevent hypernatremic dehydration and promote breast-feeding.
在纯母乳喂养的足月儿中验证高钠血症性脱水的发生率，并确定可能干扰成功母乳喂养的母体和/或婴儿因素。
我们前瞻性纳入了1999年10月至2000年3月期间转诊至我们新生儿科的所有健康母乳喂养新生儿。所有体重减轻≥出生体重10%的新生儿均进行了母乳喂养测试，并测定了血清钠、尿素和碱剩余。采用学生t检验和卡方检验对数据进行统计分析。
686例新生儿中，53例（7.7%）体重减轻≥出生体重的10%，其中19例还患有高钠血症。与体重减轻<10%的新生儿相比，这53例新生儿剖宫产发生率显著更高，母亲受教育程度更低。
我们的前瞻性研究表明，出生后最初几天体重减轻≥10%很常见。每日体重评估、仔细的母乳喂养评估以及产后早期常规随访是预防高钠血症性脱水和促进母乳喂养的有效方法。
