Adeniji K A, Anjorin A S
Department of Pathology, Faculty of Health Sciences, University of Ilorin, Kwara State, Nigeria.
Afr J Med Med Sci. 2000 Sep-Dec;29(3-4):233-7.
A review was carried out on the histopathological diagnosis of peripheral lymph node biopsies processed and reported within a period of 18 years (1979-1996) in the Department of Pathology of University of Ilorin Teaching Hospital, Ilorin, Nigeria. A total of 751 cases from 468 male and 283 female patients within the age range of 1 year to 80 years were reviewed. Non-neoplastic lesions made up 50.8% while neoplastic lesions constituted 49.2%. Tuberculosis was the commonest cause of peripheral lymphadenopathy (31.4%) followed by metastatic lesions (19.3%). As a group, the lymphomas constituted 28.2% and were made up of Hodgkin's disease 12.6%, non-Hodgkin's lymphoma including Burkitt's lymphoma 15.6% (with Burkitt's alone constituting 3.3%). Few other infectious diseases found included toxoplasmosis, histoplasmosis and onchocerciasis. Non-specific reactive and inflammatory changes (both acute and chronic) collectively formed 17.6%. The primary sites of lymph node metastases could not be determined in 36.6% of netastatic lesions while the breast was the origin in 13.8% and was the highest incidence of metastatis. The commonest lymph node group affected was the cervical (42.6%) followed by inguinal (24.1%).
对尼日利亚伊洛林大学教学医院病理科在18年（1979 - 1996年）期间处理并报告的外周淋巴结活检组织病理学诊断进行了回顾。共回顾了468例男性和283例女性患者的751例病例，年龄范围为1岁至80岁。非肿瘤性病变占50.8%，而肿瘤性病变占49.2%。结核病是外周淋巴结病最常见的原因（31.4%），其次是转移性病变（19.3%）。淋巴瘤作为一个群体占28.2%，其中霍奇金病占12.6%，非霍奇金淋巴瘤包括伯基特淋巴瘤占15.6%（仅伯基特淋巴瘤占3.3%）。发现的其他少数传染病包括弓形虫病、组织胞浆菌病和盘尾丝虫病。非特异性反应性和炎症性改变（急性和慢性）共占17.6%。36.6%的转移性病变无法确定淋巴结转移的原发部位，而乳腺是13.8%转移病例的起源部位，是转移发生率最高的部位。最常受累的淋巴结组是颈部（42.6%），其次是腹股沟（24.1%）。
