DNA修复：Ku蛋白如何实现双链末端连接。
DNA repair: how Ku makes ends meet.
作者信息
Doherty A J, Jackson S P
机构信息
Cambridge Institute for Medical Research, Department of Haematology, University of Cambridge, Hills Road, Cambridge CB2 2XY, UK.
出版信息
Curr Biol. 2001 Nov 13;11(22):R920-4. doi: 10.1016/s0960-9822(01)00555-3.
Abstract
The recently determined crystal structure of the Ku heterodimer, in both DNA-bound and unbound forms, has shed new light on the mechanism by which this protein fulfills its key role in the repair of DNA double-strand breaks.
摘要
最近确定的 Ku 异源二聚体的晶体结构，包括与 DNA 结合和未结合的形式，为这种蛋白质在 DNA 双链断裂修复中发挥关键作用的机制提供了新的线索。
Zotero 插件