Yoshino M, Uemura M, Takahashi K, Watanabe N, Hoshi H, Ohuchi K, Nakamura M, Fujita H, Sakamoto T, Takatani S
Department of Mechanical Engineering, College of Science and Technology, Nihon University, Tokyo, Japan.
Artif Organs. 2001 Sep;25(9):683-7. doi: 10.1046/j.1525-1594.2001.06856.x.
In order to develop a centrifugal blood pump that meets the requirements of a long-term, implantable circulatory support device, in this study a single-pivot bearing supported centrifugal blood pump was designed to evaluate its basic performance. The single-pivot structure consisted of a ceramic ball male pivot mounted on the bottom surface of the impeller and a polyethylene female pivot incorporated in the bottom pump casing. The follower magnet mounted inside the impeller was magnetically coupled to the driver magnet mounted on the shaft of the direct current brushless motor. As the motor rotated, the impeller rotated supported entirely by a single-pivot bearing system. The static pump performance obtained in the mock circulatory loop revealed an acceptable performance as a left ventricular assist device in terms of flow and head pressure. The pump flow of 5 L/min against the head pressure of 100 mm Hg was obtained at rotational speeds of 2,000 to 2,200 rpm. The maximum pump flow was 9 L/min with 2,200 rpm. The maximum electrical-to-hydraulic power conversion efficiency was around 14% at pump flows of 4 to 5 L/min. The stability of the impeller was demonstrated at the pump rpm higher than 1,400 with a single-pivot bearing without an additional support at its top. The single-pivot supported centrifugal pump can provide adequate flow and pressure as a ventricular assist device, but its mechanical stability and hemolytic as well as thrombotic performances must be tested prior to clinical use.
为了开发一种满足长期可植入循环支持装置要求的离心血泵，在本研究中设计了一种单枢轴轴承支撑的离心血泵，以评估其基本性能。单枢轴结构由安装在叶轮底表面的陶瓷球阳枢轴和安装在泵体底部的聚乙烯阴枢轴组成。安装在叶轮内部的从动磁体与安装在直流无刷电机轴上的驱动磁体磁耦合。随着电机旋转，叶轮在单枢轴轴承系统的完全支撑下旋转。在模拟循环回路中获得的静态泵性能表明，作为左心室辅助装置，在流量和扬程压力方面具有可接受的性能。在2000至2200转/分钟的转速下，获得了5升/分钟的泵流量，扬程压力为100毫米汞柱。最大泵流量为9升/分钟，转速为2200转/分钟。在泵流量为4至5升/分钟时，最大电-液功率转换效率约为14%。在高于1400转/分钟的泵转速下，单枢轴轴承在其顶部没有额外支撑的情况下，叶轮的稳定性得到了证明。单枢轴支撑的离心泵作为心室辅助装置可以提供足够的流量和压力，但其机械稳定性、溶血性能和血栓形成性能在临床使用前必须进行测试。
