Foster J H, Maxwell M H, Franklin S S, Bleifer K H, Trippel O H, Julian O C, DeCamp P T, Varady P T
JAMA. 1975 Mar 10;231(10):1043-8.
The blood pressure response to operative treatment in 502 patients with renal artery stenosis and coexisting hypertension was as follows: 51% cured, 15% improved, and 34% failure. The operative mortality was 5.9%. Patients with unilateral fibromuscular disease had a favorable blood pressure response (79.8%) more frequently than the patients with unilateral atherosclerosis (63.4%). In patients with bilateral stenosis, a favorable result occurred in 56%. The anatomic failure rate due to thrombosis of arterial reconstructions, as well as the operative mortality, varied considerably between institutions. If preoperative diagnostic studies demonstrated significant functional disparity between kidneys, and if the operation was anatomically successful, then approximately 80% of these patients were benefited by surgical intervention.
502例肾动脉狭窄合并高血压患者手术治疗后的血压反应如下:51%治愈,15%改善,34%失败。手术死亡率为5.9%。单侧纤维肌性疾病患者的血压反应良好率(79.8%)高于单侧动脉粥样硬化患者(63.4%)。双侧狭窄患者中,56%取得了良好效果。动脉重建血栓形成导致的解剖学失败率以及手术死亡率在不同机构之间差异很大。如果术前诊断研究显示双肾之间存在明显的功能差异,且手术在解剖学上成功,那么这些患者中约80%可从手术干预中获益。