全髋关节置换术后异位骨化的预防：60例患者中吲哚美辛与鲑鱼降钙素的前瞻性比较

Prevention of heterotopic ossification after total hip replacement: a prospective comparison of indomethacin and salmon calcitonin in 60 patients.

作者信息

Günal I, Hazer B, Seber S, Göktürk E, Turgut A, Köse N

机构信息

Department of Orthopedics, Dokuz Eylül University Hospital, Izmir, Turkey.

出版信息

Acta Orthop Scand. 2001 Oct;72(5):467-9. doi: 10.1080/000164701753532781.

DOI:10.1080/000164701753532781

PMID:11728072

Abstract

We did a prospective consecutive study of prophylaxis for heterotopic ossification (HO) comparing indomethacin (100 mg/day) and salmon calcitonin (3 MRC-U/kg/day) for 14 days. Each group consisted of 30 patients. 19 patients in the indomethacin group and 2 in the calcitonin group developed HO. We conclude that use of calcitonin in the prophylaxis of HO after total hip replacement is more effective than indomethacin.

摘要

我们进行了一项关于异位骨化（HO）预防的前瞻性连续研究，比较了吲哚美辛（100毫克/天）和鲑鱼降钙素（3 MRC - U/千克/天），疗程为14天。每组由30名患者组成。吲哚美辛组有19名患者发生HO，降钙素组有2名患者发生HO。我们得出结论，全髋关节置换术后使用降钙素预防HO比吲哚美辛更有效。