Thirumalai S, Abou-Khalil B, Fakhoury T, Suresh G
Children's Hospital, Los Angeles, CA, USA.
Dev Med Child Neurol. 2001 Nov;43(11):731-4. doi: 10.1017/s0012162201001335.
Video-EEG monitoring was performed to evaluate 193 children (91 females, 102 males; mean age 9.6 years, SD 5.7) who presented with paroxysmal events of uncertain etiology. Diagnosis of the type of event, i.e. epileptic or non-epileptic, was successfully established in 130 of 193 patients (67.3%). Seventy children (36%) had mental retardation* (MR). Children with MR were more likely (p<0.05) than children without MR to have events during the studies. Children with and without MR had strikingly similar frequencies of epileptic and non-epileptic events. In participants who had events recorded and characterized, epileptic seizures were identified in 67 children (51.5%), non-epileptic events in 54 children (41.5%), and both epileptic and non-epileptic events in nine children (7%). Improved diagnosis prompted appropriate management. This should encourage more frequent use of video-EEG in children, especially in those with MR, to differentiate epilepsy from behavioral disturbances so that specific treatment can be provided.
对193名病因不明的阵发性事件患儿（91名女性，102名男性；平均年龄9.6岁，标准差5.7）进行了视频脑电图监测。193例患者中有130例（67.3%）成功确诊事件类型，即癫痫性或非癫痫性。70名儿童（36%）有智力障碍*（MR）。与无智力障碍的儿童相比，有智力障碍的儿童在研究期间发生事件的可能性更大（p<0.05）。有和无智力障碍的儿童癫痫性和非癫痫性事件的发生率惊人地相似。在有事件记录并定性的参与者中，67名儿童（51.5%）被确定为癫痫发作，54名儿童（41.5%）为非癫痫性事件，9名儿童（7%）既有癫痫性事件又有非癫痫性事件。诊断的改善促使了适当的治疗。这应该鼓励更频繁地对儿童，尤其是有智力障碍的儿童使用视频脑电图，以区分癫痫与行为障碍，从而提供特定的治疗。
