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继发性甲状旁腺功能亢进。肾功能不全患者的保守治疗。

Secondary hyperparathyroidism. Conservative management in patients with renal insufficiency.

作者信息

Popovtzer M M, Pinggera W F, Robinette J B

出版信息

JAMA. 1975 Mar 3;231(9):960-2. doi: 10.1001/jama.231.9.960.

DOI:10.1001/jama.231.9.960
PMID:1173103
Abstract

In three patients with advanced renal disease (inulin clearance, 4.6 to 9.1 ml/min) and systemic manifestations of secondary hyperparathyroidism, concentrations of serum calcium and phosphorus were maintained within our normal limits (9 and 3.5 mg/100 ml, respectively) with phosphate-binding antacids and orally given calcium carbonate. The result was progressive disappearance of symptoms related to secondary hyperparathyroidism, healing of osteitis fibrosa, and normalization of serum concentrations of immunoreactive parathyroid hormone.

摘要

在3例晚期肾病患者(菊粉清除率为4.6至9.1毫升/分钟)伴有继发性甲状旁腺功能亢进的全身表现,通过使用磷酸盐结合抗酸剂和口服碳酸钙,血清钙和磷的浓度维持在我们设定的正常范围内(分别为9毫克/100毫升和3.5毫克/100毫升)。结果是与继发性甲状旁腺功能亢进相关的症状逐渐消失,纤维性骨炎愈合,以及免疫反应性甲状旁腺激素的血清浓度恢复正常。

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