Kolendorf K, Hansen J B, Engberg L, Friis T, Lindenberg J
Acta Chir Scand. 1975;141(1):20-3.
The diagnostic value of cytological, serological and scintigraphical examination was evaluated in 20 histologically verified cases of thyroid disorder. The predictive values of specificity as to malignancy, thyroiditis and thyroid autoantibodies were respectively 0 percent (0-71), 80 percent (28-99) and 75 percent (19-99), and the predictive values of sensitivity were 88 percent (64-99), 100 percent (78-100) and 94 percent (70-100). Cold nodules were malignant in 40 percent. Fine needle biopsy can be used as a supplementary test without any risks and is a valuable aid in the diagnosis of Hashimoto's thyroiditis, but not in the diagnosis of malignant lesions. If any clinical or scintigraphical (cold nodule) suspicion of malignancy exists, a surgical biopsy must be done.
对20例经组织学证实的甲状腺疾病病例评估了细胞学、血清学和闪烁扫描检查的诊断价值。对恶性肿瘤、甲状腺炎和甲状腺自身抗体的特异性预测值分别为0%（0 - 71）、80%（28 - 99）和75%（19 - 99），敏感性预测值分别为88%（64 - 99）、100%（78 - 100）和94%（70 - 100）。冷结节中有40%为恶性。细针活检可作为一项无任何风险的补充检查，对桥本甲状腺炎的诊断有重要帮助，但对恶性病变的诊断无帮助。如果临床或闪烁扫描（冷结节）怀疑有恶性肿瘤，必须进行手术活检。
