促甲状腺激素β亚基的致突眼活性
Exophthalmogenic activity of the beta subunit of thyrotropin.
作者信息
Kohn L D, Winand R J
出版信息
Endocrinology. 1975 Jun;96(6):1592-4. doi: 10.1210/endo-96-6-1592.
PMID:1173233
Abstract
The exophthalmogenic activity of the beta subunit of bovine thyrotropin is only 10% to 20% that of the thyrotropin molecule or of an exophthalmogenic factor produced by partial pepsin digestion of purified thyrotropin preparations. The alpha subunit of thyrotropin, luteinizing hormone, and both subunits of luteinizing hormone have no exophthalmogenic activity.
摘要
牛促甲状腺激素β亚基的致突眼活性仅为促甲状腺激素分子或经部分胃蛋白酶消化纯化促甲状腺激素制剂所产生的致突眼因子的10%至20%。促甲状腺激素的α亚基、促黄体生成素以及促黄体生成素的两个亚基均无致突眼活性。
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