Dass A B, Ferrone P J, Chu Y R, Esposito M, Gray L
Associated Retinal Consultants, P.C. , R6007 Reichert Health Building, 5333 McAuley Drive, Ypsilanti, MI 48197, USA.
Ophthalmology. 2001 Dec;108(12):2326-8. doi: 10.1016/s0161-6420(01)00808-9.
The purpose of this study is to determine whether 3-mm computed tomography (CT) cuts are equivalent to 1-mm CT cuts for detecting small intraocular foreign bodies (IOFBs).
Experimental instrument validation study.
Seventy-two porcine eyes were divided into three groups. Each group had 0.5 ml of human blood injected into the vitreous cavity and were surgically implanted with IOFBs.
Each eye was surgically implanted with 0.5-mm metallic, 0.5-mm glass, or 0.5-mm stone IOFBs. Two additional eyes were left without IOFBs to serve as negative controls.
Axial CT images of both 3-mm and 1-mm thickness were obtained and analyzed in masked fashion by two separate neuroradiologists.
The sensitivity for detecting 0.5-mm metallic, 0.5-mm glass, and 0.5-mm stone IOFBs with 3-mm CT images was 100%. The sensitivity for detecting 0.5-mm metallic, 0.5-mm glass, and 0.5-mm stone IOFBs with 1-mm CT images was also 100% (confidence interval, 95%; range, 0.88-1.00). Two negative control eyes without IOFBs were also correctly evaluated by the neuroradiologists.
With modern spiral CT scanning, 3-mm cuts are as sensitive as 1-mm cuts for detecting small metallic, glass, and stone IOFBs.
本研究旨在确定3毫米计算机断层扫描（CT）切片在检测眼内小异物（IOFBs）方面是否等同于1毫米CT切片。
实验仪器验证研究。
72只猪眼被分为三组。每组向玻璃体腔注射0.5毫升人血，并通过手术植入眼内异物。
每只眼睛通过手术植入0.5毫米的金属、0.5毫米的玻璃或0.5毫米的石头眼内异物。另外两只眼睛不植入眼内异物作为阴性对照。
获得3毫米和1毫米厚度的轴向CT图像，并由两名独立的神经放射科医生以盲法进行分析。
3毫米CT图像检测0.5毫米金属、0.5毫米玻璃和0.5毫米石头眼内异物的灵敏度为100%。1毫米CT图像检测0.5毫米金属、0.5毫米玻璃和0.5毫米石头眼内异物的灵敏度也为100%（置信区间，95%；范围，0.88 - 1.00）。两名神经放射科医生也正确评估了两只无眼内异物的阴性对照眼。
对于检测小的金属、玻璃和石头眼内异物，使用现代螺旋CT扫描时，3毫米切片与1毫米切片的灵敏度相同。
