Jacobs P, Chalmers I M, Kahn L B
S Afr Med J. 1975 Apr 19;49(17):715-7.
The association of IgG monoclonal gammopathy with lymphocytic lymphoma and chronic lymphocytic leukaemia is reported. Although rare, such immunoglobulin synthesis may have prognostic importance and is of value in monitoring the effect of therapy. The morphological features which should draw attention to this pattern of protein abnormality are briefly reviewed. This finding emphasises the histogenesis of these tumours from the immune system and questions their classification on a purely morphological basis.
据报道，IgG单克隆丙种球蛋白病与淋巴细胞淋巴瘤及慢性淋巴细胞白血病有关。尽管这种情况罕见，但这种免疫球蛋白合成可能具有预后意义，且对监测治疗效果有价值。本文简要回顾了应引起对这种蛋白质异常模式关注的形态学特征。这一发现强调了这些肿瘤源自免疫系统的组织发生学，并对基于纯粹形态学的分类提出了质疑。
