Haendle J
Mutat Res. 1979 Oct;62(3):467-75. doi: 10.1016/0027-5107(79)90042-3.
By using suitably marked X-chromosomes it was possible, on the one hand, to distinguish between induced mitotic recombination in euchromatin and in heterochromatin and, on the other hand, to get some ideas about the distribution of the recombination events within the euchromatin. These results have been taken as a basis for discussing the question: To what extent is induced mitotic recombination a simple breakage-fusion mechanism and to what extent is it comparable to meiotic recombination? Furthermore, the results give evidence that must be considered when recombination data are used to make mitotic maps.
通过使用经过适当标记的X染色体,一方面能够区分常染色质和异染色质中诱导的有丝分裂重组,另一方面可以对常染色质内重组事件的分布有所了解。这些结果已被用作讨论以下问题的基础:诱导的有丝分裂重组在多大程度上是一种简单的断裂-融合机制,以及在多大程度上它与减数分裂重组具有可比性?此外,这些结果提供了在利用重组数据绘制有丝分裂图谱时必须考虑的证据。