Wardlaw S, Lauersen N H, Saxena B B
Acta Endocrinol (Copenh). 1975 Jul;79(3):568-76. doi: 10.1530/acta.0.0790568.
Receptors specific for hCG were found in human corpora lutea and follicles. hCG and LH were found to bind at a similar receptor site. The dissociation constant for hCG ranged from 10-minus 10 to 10-minus 11 mol/1 in human corpora lutea. The number of binding sites for 125-I-hCG ranged from 10-minus 14 to 10-minus 15 moles/mg protein in human corpora lutea. The binding of 125-I-hCG to ovary was found to vary at different stages of the menstrual cycle. The binding of 125-I-hCG to human ovaries increased on days 13-15 of the cycle, then declined slightly, and increased again on days 22-23. Following day 23, there was a slow decline until day 27 when binding activity could no longer be measured. No binding could be measured by the corpus luteum after the onset of menstruation or in corpora albicans.
在人类黄体和卵泡中发现了特异性针对人绒毛膜促性腺激素（hCG）的受体。发现hCG和促黄体生成素（LH）在相似的受体位点结合。在人类黄体中，hCG的解离常数范围为10的负10次方至10的负11次方摩尔/升。在人类黄体中，125-I-hCG的结合位点数范围为10的负14次方至10的负15次方摩尔/毫克蛋白质。发现125-I-hCG与卵巢的结合在月经周期的不同阶段有所变化。125-I-hCG与人类卵巢的结合在周期的第13至15天增加，然后略有下降，并在第22至23天再次增加。在第23天之后，结合活性缓慢下降，直到第27天无法再测量到结合活性。月经开始后，黄体或白体中无法测量到结合。
