McNeilly A S, Kerin J, Swanston I A, Bramley T A, Baird D T
J Endocrinol. 1980 Dec;87(3):315-25. doi: 10.1677/joe.0.0870315.
The changes in the binding of human chorionic gonadotrophin/luteinizing hormone (HCG/LH), follicle-stimulating hormone (FSH) and prolactin to 44 corpora lutea have been assessed during the luteal phase of the human menstrual cycle and early pregnancy. All corpora lutea bound HCG but out of 32 only ten bound FSH and only seven bound prolactin specifically. While binding of HCG increased to maximal levels in the mid-luteal phase, binding of FSH and prolactin was most often found in the early luteal phase. Maximum binding of HCG was associated with maximum serum levels of progesterone. Luteal regression was associated with a decrease in the binding of HCG but a causal relationship could not be established. Very low binding of HCG was found to corpora lutea of pregnancy. These results show that (1) the changes in binding of HCG during the luteal phase of the human menstrual cycle are similar to those in other species and (2) there are specific binding sites for prolactin and FSH in the human corpus luteum.
在人类月经周期的黄体期和妊娠早期，已对人绒毛膜促性腺激素/促黄体生成素（HCG/LH）、促卵泡激素（FSH）和催乳素与44个黄体的结合变化进行了评估。所有黄体均结合HCG，但在32个黄体中，只有10个特异性结合FSH，只有7个特异性结合催乳素。虽然HCG的结合在黄体中期增加到最高水平，但FSH和催乳素的结合最常出现在黄体早期。HCG的最大结合与孕酮的最高血清水平相关。黄体退化与HCG结合的减少有关，但无法建立因果关系。在妊娠黄体中发现HCG的结合非常低。这些结果表明：（1）人类月经周期黄体期HCG结合的变化与其他物种相似；（2）人类黄体中存在催乳素和FSH的特异性结合位点。
