Mowat C, Stanley A J
Department of Gastroenterology, Glasgow Royal Infirmary, Glasgow, UK.
Aliment Pharmacol Ther. 2001 Dec;15(12):1851-9. doi: 10.1046/j.1365-2036.2001.01116.x.
Spontaneous bacterial peritonitis is a serious complication of cirrhotic ascites, arising most frequently in those with advanced liver disease. Its development leads to a further reduction in the effective arterial blood volume, and it has a mortality rate equivalent to that of a variceal bleed. However, problems remain with regard to the identification and optimal treatment of spontaneous bacterial peritonitis. Several important studies and consensus documents on the condition have recently been published which aid in the identification of patients at risk and help to guide therapy. In this review, we discuss these publications and address the issues of diagnosis, treatment and both primary and secondary prophylaxis of spontaneous bacterial peritonitis in the light of recent data.
自发性细菌性腹膜炎是肝硬化腹水的一种严重并发症，最常发生于晚期肝病患者。它的发生会导致有效动脉血容量进一步减少，其死亡率与静脉曲张破裂出血相当。然而，在自发性细菌性腹膜炎的识别和最佳治疗方面仍存在问题。最近发表了几项关于该病症的重要研究和共识文件，有助于识别高危患者并指导治疗。在本综述中，我们根据最新数据讨论这些出版物，并阐述自发性细菌性腹膜炎的诊断、治疗以及一级和二级预防问题。
