Tan Q, Sun K, Pan Y, Sun K, Hua C, Qiao L
Department of Neurosurgery, Jinling Hospital, Nanjing University School of Medicine, Nanjing, China.
Stereotact Funct Neurosurg. 2000;75(2-3):90-5. doi: 10.1159/000048388.
From May 1989 to April 1997, functional hemispherectomy was performed in 8 cases of intractable seizures. We retrospectively analyzed our experience to evaluate the seizure control and complications of this surgical technique.
Following Dr. Rasmussen's model of functional hemispherectomy or performing a modification of this operation, we removed the sensorimotor cortex and temporal lobe associated with disconnection of the remaining portions of the frontal lobe and parieto-occipital lobe.
All the patients were followed up for 3-11 years (mean 6.7 years). Satisfactory seizure control was obtained in all the cases. Life quality improved and patients worked or studied well after the operations. No cases of superficial cerebral hemosiderosis were found.
Modified functional hemispherectomy may allow the patients to lead more independent lives by leading to a cessation or reduced frequency of seizures.
1989年5月至1997年4月，对8例顽固性癫痫患者实施了功能性大脑半球切除术。我们回顾性分析了我们的经验，以评估这种手术技术的癫痫控制情况和并发症。
按照拉斯姆森博士的功能性大脑半球切除术模型或对该手术进行改良，我们切除了感觉运动皮层和颞叶，并切断额叶和顶枕叶的其余部分之间的联系。
所有患者均随访3 - 11年（平均6.7年）。所有病例均获得了满意的癫痫控制。术后患者生活质量改善，能够正常工作或学习。未发现浅表性脑铁沉积症病例。
改良的功能性大脑半球切除术可使患者癫痫发作停止或发作频率降低，从而过上更独立的生活。
