Heidbrink V V, Mallach H J, Moosmayer A
Arzneimittelforschung. 1975 Apr;25(4):516-7.
A gas-chromatographic method is reported which completely resolves diazepam and its major metabolites and thus enables the specific quantitation of these compounds after extraction from serum and urine. The sensitivity limits are about 3 ng/ml if 4 ml serum or urine are extracted.
报道了一种气相色谱法，该方法能完全分离地西泮及其主要代谢物，从而能够在从血清和尿液中提取后对这些化合物进行特异性定量。如果提取4毫升血清或尿液，检测限约为3纳克/毫升。
