Nakabo Satoshi, Torii Yasuhiro, Itota Toshiyuki, Ishikawa Kunio, Suzuki Kazuomi
Department of Operative Dentistry, Okayama University Dental School, Okayama, Japan.
Dent Mater. 2002 Jan;18(1):81-7. doi: 10.1016/s0109-5641(01)00024-0.
The aim of this study was to evaluate the feasibility of regulation of NaF release from bis-GMA/TEGDMA resin using gamma-methacryloxypropyltrimethoxysilane (gamma-MPTS).
NaF powder was treated with gamma-MPTS to form a polysiloxane layer on its surface. The morphology and the composition of the NaF powder treated with gamma-MPTS were evaluated using scanning electron microscopy, infrared spectroscopy, contact angle measurement and X-ray photoelectron spectroscopy. Bis-GMA/TEGDMA resin containing 50 wt% NaF powder was prepared as a model resin and immersed in distilled water at 37 degrees C, and the amount of fluoride released from the resin was measured using a fluoride electrode. The mechanical strength in terms of diametral tensile strength before and after fluoride release was also measured, and statistically analyzed using one-way factorial ANOVA and Fisher's PLSD method.
NaF powder was covered with hydrophobic gamma-MPTS delivered polysiloxane. A larger amount of fluoride was released at the initial stage from the resin containing NaF treated with no gamma-MPTS. However, fluoride release terminated in a relatively shorter period. In contrast, we observed a smaller amount of fluoride released for a longer period from the resin containing NaF treated with gamma-MPTS.
We found that gamma-MPTS treatment is useful for the regulation of NaF release from bis-GMA/TEGDMA resin. The mechanism of slow NaF release may be the formation of a hydrophobic polysiloxane layer on the surface of NaF powder and resulting slow water diffusion to NaF powder.
本研究旨在评估使用γ-甲基丙烯酰氧基丙基三甲氧基硅烷（γ-MPTS）调节双酚A-甲基丙烯酸缩水甘油酯/三乙二醇二甲基丙烯酸酯（bis-GMA/TEGDMA）树脂中氟化钠（NaF）释放的可行性。
用γ-MPTS处理NaF粉末，以在其表面形成聚硅氧烷层。使用扫描电子显微镜、红外光谱、接触角测量和X射线光电子能谱对经γ-MPTS处理的NaF粉末的形态和组成进行评估。制备含50 wt% NaF粉末的bis-GMA/TEGDMA树脂作为模型树脂，并将其浸入37℃的蒸馏水中，使用氟电极测量从树脂中释放的氟量。还测量了氟释放前后树脂的径向拉伸强度方面的机械强度，并使用单向因子方差分析和Fisher最小显著差异法进行统计分析。
NaF粉末被疏水性的由γ-MPTS传递的聚硅氧烷覆盖。在初始阶段，未用γ-MPTS处理的含NaF树脂释放出大量的氟。然而，氟释放终止于相对较短的时间内。相比之下，我们观察到用γ-MPTS处理的含NaF树脂在较长时间内释放出较少的氟。
我们发现γ-MPTS处理对于调节bis-GMA/TEGDMA树脂中NaF的释放是有用的。NaF缓慢释放的机制可能是在NaF粉末表面形成疏水性聚硅氧烷层以及由此导致的水向NaF粉末的扩散缓慢。
