Weiss R E, Hartanto V, Perrotti M, Cummings K B, Bykanov A N, Egorov V, Sobolevsky S A
Division of Urology, Robert Wood Johnson Medical School, New Brunswick, New Jersey, USA.
Urology. 2001 Dec;58(6):1059-63. doi: 10.1016/s0090-4295(01)01407-8.
To compare the sensitivity and accuracy of the mechanical imaging system (MI system) to that of the simulated digital rectal examination (DRE) in detecting nodules within fabricated rubber prostate phantoms. Mechanical imaging is a new technology for visualizing and characterizing tissues using mechanical strain and stress data.
Twelve rubber phantoms were designed to simulate human prostates. Ten phantoms contained hard nodules in various locations. Two phantoms contained no nodules. Each model was examined with the MI system by a urologist (R.E.W.) and research student. Three-dimensional images of the examined prostate phantoms with and without nodules were generated by the MI system software. Blind DRE was performed on each phantom independently by the urologist and student. The results of the MI examinations and DREs were compared for sensitivity in detecting the presence and location of nodules within the prostate phantoms.
Three-dimensional MI images reconstructed from both the student and the urologist examination data demonstrated 100% of the nodules in the appropriate locations. The DREs by the urologist detected 83% of the nodules in the appropriate locations. The DREs by the student detected 67% of the nodules in the appropriate locations.
The prostate MI system allowed the detection of nodules in the prostate phantoms with sensitivity exceeding that of an experienced urologist. In contrast to the DRE, the results of the MI examination appear to be independent of the operator's experience. Therefore, the MI system is a promising means of accurate, sensitive, objective, and recordable detection of hard nodules within the prostate.
比较机械成像系统（MI系统）与模拟数字直肠指检（DRE）在检测人造橡胶前列腺模型中的结节时的敏感性和准确性。机械成像是一种利用机械应变和应力数据对组织进行可视化和特征描述的新技术。
设计了12个橡胶模型来模拟人体前列腺。10个模型在不同位置含有硬结节。2个模型不含结节。泌尿科医生（R.E.W.）和一名研究生使用MI系统对每个模型进行检查。MI系统软件生成了有结节和无结节的前列腺模型的三维图像。泌尿科医生和研究生分别对每个模型独立进行盲法DRE。比较MI检查和DRE在检测前列腺模型中结节的存在和位置方面的敏感性结果。
根据学生和泌尿科医生的检查数据重建的三维MI图像在适当位置显示出100%的结节。泌尿科医生进行的DRE在适当位置检测到83%的结节。学生进行的DRE在适当位置检测到67%的结节。
前列腺MI系统能够检测前列腺模型中的结节，其敏感性超过经验丰富的泌尿科医生。与DRE不同，MI检查的结果似乎与操作者的经验无关。因此，MI系统是一种有前景的方法，可用于准确、敏感、客观且可记录地检测前列腺内的硬结节。
