Trupiano J K, Prayson R A
Department of Anatomic Pathology, Cleveland Clinic Foundation, Cleveland, OH 44195, USA.
Ann Diagn Pathol. 2001 Dec;5(6):350-3. doi: 10.1053/adpa.2001.29343.
Atypical mycobacterial infections of the middle ear are extremely rare. To our knowledge, only eight cases have been reported in the literature, five of which involve Mycobacterium avium intracellulare. We present a case of culture-proven, M. avium intracellulare otomastoiditis in an 8-year-old boy with common variable immunodeficiency syndrome. The patient clinically presented with pain and otorrhea. The histopathology was marked by acid-fast bacilli-laden histiocytes. Consideration of this entity in the differential diagnosis of chronic, recalcitrant otorrhea can lead to timely diagnosis, treatment, an decreased morbidity.
中耳非典型分枝杆菌感染极为罕见。据我们所知，文献中仅报道过8例，其中5例涉及鸟分枝杆菌胞内菌。我们报告1例经培养证实的鸟分枝杆菌胞内菌引起的耳乳突炎病例，患者为1名患有常见可变免疫缺陷综合征的8岁男孩。该患者临床上表现为疼痛和耳漏。组织病理学表现为充满抗酸杆菌的组织细胞。在慢性顽固性耳漏的鉴别诊断中考虑到这种疾病，可实现及时诊断、治疗并降低发病率。
