西澳大利亚州关于卵巢癌整块切除并同期行乙状结肠直肠切除术的经验。
The Western Australian experience of the use of en bloc resection of ovarian cancer with concomitant rectosigmoid colectomy.
作者信息
Clayton R D, Obermair A, Hammond I G, Leung Y C, McCartney A J
机构信息
Western Australian Gynaecologic Cancer Service, King Edward Memorial Hospital, 374 Bagot Road, Subiaco, Perth, 6008, Western Australia.
出版信息
Gynecol Oncol. 2002 Jan;84(1):53-7. doi: 10.1006/gyno.2001.6469.
OBJECTIVES
The aim of this study was to assess the technique of en bloc resection of ovarian cancer with concomitant rectosigmoid colectomy, in relation to perioperative complication rates, and its impact on survival following the procedure.
METHODS
A retrospective review was performed of the case notes of 129 consecutive procedures performed between 1989 and 2000 in a regional cancer center. RESULTS. Overall, 48.8% of patients suffered a major or minor complication. Complications relating to bowel anastomosis occurred in 2.4%. Perioperative mortality was 3.1%. Median survival for the group as a whole was 30.6 months. Patients who were optimally debulked had a significantly longer median survival time.
CONCLUSION
En bloc resection of ovarian cancer with concomitant rectosigmoid colectomy allows a high rate of optimal debulking with acceptable morbidity, mortality, and survival.
目的
本研究旨在评估卵巢癌联合乙状结肠直肠切除术的整块切除技术，及其与围手术期并发症发生率的关系，以及该手术对术后生存的影响。
方法
对1989年至2000年在某地区癌症中心连续进行的129例手术的病历进行回顾性分析。结果：总体而言，48.8%的患者出现了严重或轻微并发症。肠吻合相关并发症发生率为2.4%。围手术期死亡率为3.1%。整个组的中位生存期为30.6个月。达到最佳肿瘤细胞减灭术的患者中位生存时间显著更长。
结论
卵巢癌联合乙状结肠直肠切除术的整块切除可实现较高比例的最佳肿瘤细胞减灭术，且具有可接受的发病率、死亡率和生存率。
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