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Enzymology. Coenzymes and radicals.

作者信息

Frey P A

机构信息

Department of Biochemistry, University of Wisconsin-Madison, Madison, WI 53705, USA.

出版信息

Science. 2001 Dec 21;294(5551):2489-90. doi: 10.1126/science.1067916.

DOI:10.1126/science.1067916

PMID:11752561

Abstract

摘要

相似文献

Enzymology. Coenzymes and radicals.

Science. 2001 Dec 21;294(5551):2489-90. doi: 10.1126/science.1067916.

Crystal structure of the free radical intermediate of pyruvate:ferredoxin oxidoreductase.

Science. 2001 Dec 21;294(5551):2559-63. doi: 10.1126/science.1066198.

Mechanism of the Clostridium thermoaceticum pyruvate:ferredoxin oxidoreductase: evidence for the common catalytic intermediacy of the hydroxyethylthiamine pyropyrosphate radical.

Biochemistry. 1997 Jul 15;36(28):8484-94. doi: 10.1021/bi970403k.

Structure and electron transfer mechanism of pyruvate:ferredoxin oxidoreductase.

Curr Opin Struct Biol. 1999 Dec;9(6):663-9. doi: 10.1016/s0959-440x(99)00027-5.

Binding site for coenzyme A revealed in the structure of pyruvate:ferredoxin oxidoreductase from .

Proc Natl Acad Sci U S A. 2018 Apr 10;115(15):3846-3851. doi: 10.1073/pnas.1722329115. Epub 2018 Mar 26.

Crystal structures of the key anaerobic enzyme pyruvate:ferredoxin oxidoreductase, free and in complex with pyruvate.

Nat Struct Biol. 1999 Feb;6(2):182-90. doi: 10.1038/5870.

Radical reactions of thiamin pyrophosphate in 2-oxoacid oxidoreductases.

Biochim Biophys Acta. 2012 Nov;1824(11):1291-8. doi: 10.1016/j.bbapap.2011.11.010. Epub 2011 Dec 8.

Snapshots of three intermediates at the active site of pyruvate oxidase.

Nat Chem Biol. 2006 Jun;2(6):294-5. doi: 10.1038/nchembio0606-294.

Pyruvate ferredoxin oxidoreductase and its radical intermediate.

Chem Rev. 2003 Jun;103(6):2333-46. doi: 10.1021/cr020423e.

The catalytic cycle of a thiamin diphosphate enzyme examined by cryocrystallography.

Nat Chem Biol. 2006 Jun;2(6):324-8. doi: 10.1038/nchembio788. Epub 2006 May 7.

引用本文的文献

Radical reactions of thiamin pyrophosphate in 2-oxoacid oxidoreductases.

Biochim Biophys Acta. 2012 Nov;1824(11):1291-8. doi: 10.1016/j.bbapap.2011.11.010. Epub 2011 Dec 8.

EPR spectroscopic and computational characterization of the hydroxyethylidene-thiamine pyrophosphate radical intermediate of pyruvate:ferredoxin oxidoreductase.

Biochemistry. 2006 Jun 13;45(23):7122-31. doi: 10.1021/bi0602516.

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Enzymology. Coenzymes and radicals.

作者信息

Frey P A

机构信息

Department of Biochemistry, University of Wisconsin-Madison, Madison, WI 53705, USA.

出版信息

Science. 2001 Dec 21;294(5551):2489-90. doi: 10.1126/science.1067916.

DOI:10.1126/science.1067916

PMID:11752561

Abstract

摘要

相似文献

Enzymology. Coenzymes and radicals.

Science. 2001 Dec 21;294(5551):2489-90. doi: 10.1126/science.1067916.

Crystal structure of the free radical intermediate of pyruvate:ferredoxin oxidoreductase.

Science. 2001 Dec 21;294(5551):2559-63. doi: 10.1126/science.1066198.

Mechanism of the Clostridium thermoaceticum pyruvate:ferredoxin oxidoreductase: evidence for the common catalytic intermediacy of the hydroxyethylthiamine pyropyrosphate radical.

Biochemistry. 1997 Jul 15;36(28):8484-94. doi: 10.1021/bi970403k.

Structure and electron transfer mechanism of pyruvate:ferredoxin oxidoreductase.

Curr Opin Struct Biol. 1999 Dec;9(6):663-9. doi: 10.1016/s0959-440x(99)00027-5.

Binding site for coenzyme A revealed in the structure of pyruvate:ferredoxin oxidoreductase from .

Proc Natl Acad Sci U S A. 2018 Apr 10;115(15):3846-3851. doi: 10.1073/pnas.1722329115. Epub 2018 Mar 26.

Crystal structures of the key anaerobic enzyme pyruvate:ferredoxin oxidoreductase, free and in complex with pyruvate.

Nat Struct Biol. 1999 Feb;6(2):182-90. doi: 10.1038/5870.

Radical reactions of thiamin pyrophosphate in 2-oxoacid oxidoreductases.

Biochim Biophys Acta. 2012 Nov;1824(11):1291-8. doi: 10.1016/j.bbapap.2011.11.010. Epub 2011 Dec 8.

Snapshots of three intermediates at the active site of pyruvate oxidase.

Nat Chem Biol. 2006 Jun;2(6):294-5. doi: 10.1038/nchembio0606-294.

Pyruvate ferredoxin oxidoreductase and its radical intermediate.

Chem Rev. 2003 Jun;103(6):2333-46. doi: 10.1021/cr020423e.

The catalytic cycle of a thiamin diphosphate enzyme examined by cryocrystallography.

Nat Chem Biol. 2006 Jun;2(6):324-8. doi: 10.1038/nchembio788. Epub 2006 May 7.

引用本文的文献

Radical reactions of thiamin pyrophosphate in 2-oxoacid oxidoreductases.

Biochim Biophys Acta. 2012 Nov;1824(11):1291-8. doi: 10.1016/j.bbapap.2011.11.010. Epub 2011 Dec 8.

EPR spectroscopic and computational characterization of the hydroxyethylidene-thiamine pyrophosphate radical intermediate of pyruvate:ferredoxin oxidoreductase.

Biochemistry. 2006 Jun 13;45(23):7122-31. doi: 10.1021/bi0602516.