白三烯受体拮抗剂——特应性皮炎的一种新型治疗方法？

Leukotriene receptor antagonists--a novel therapeutic approach in atopic dermatitis?

作者信息

Kägi M K

机构信息

Private Praxis for Dermatology, Allergy and Clinical Immunology, Zürich, Switzerland.

出版信息

Dermatology. 2001;203(4):280-3. doi: 10.1159/000051772.

DOI:10.1159/000051772

PMID:11752812

Abstract

Cysteinyl leukotrienes have been shown to be important in the pathogenesis of both asthma and rhinitis. Improvement of skin manifestations in atopic dermatitis has been reported with leukotriene receptor antagonists. This article reviews current data on the experimental evidence and clinical efficacy of leukotriene receptor antagonists in the treatment of atopic dermatitis.

摘要

半胱氨酰白三烯已被证明在哮喘和鼻炎的发病机制中都很重要。有报道称，白三烯受体拮抗剂可改善特应性皮炎的皮肤表现。本文综述了白三烯受体拮抗剂治疗特应性皮炎的实验证据和临床疗效的现有数据。