Miller A
Environ Health Perspect. 1975 Jun;11:243-6. doi: 10.1289/ehp.7511243.
Simple tests based on a voluntary forced expiration can detect pulmonary impairment of occupational or environmental origin earlier than can be done using clinical or radiographic examination. These tests are easily performed and repeated, require little time and can be readily set up in the field. Flow impairment ("obstructive") has conventionally been measured by the forced expiratory volume--1 sec (FEV1); earlier changes, in the small airways are more likely to be detected by the maximal mid-expiratory flow (MMF) and the maximum expiratory flow-volume (MEFV) curve at low lung volumes. Volume impairment ("restrictive") is detected by the forced vital capacity (FVC) from which the preceding measurements are made.
基于自愿用力呼气的简单测试比临床或影像学检查能更早地检测出职业性或环境性起源的肺损伤。这些测试易于执行和重复,所需时间少,且能在现场轻松设置。气流受损(“阻塞性”)传统上通过第1秒用力呼气量(FEV1)来测量;小气道的早期变化更有可能通过最大呼气中期流速(MMF)和低肺容积时的最大呼气流量-容积(MEFV)曲线检测到。容积受损(“限制性”)通过用力肺活量(FVC)检测,之前的测量均基于此。