Trick G L, Bhatt S S, Dahl D, Skarf B
Department of Eye Care Services, Henry Ford Health Sciences Center, Detroit, Michigan, 48202, USA.
J Neuroophthalmol. 2001 Dec;21(4):240-4. doi: 10.1097/00041327-200112000-00002.
To determine if confocal scanning laser (CSL) tomography can quantify optic disc topography in patients with pseudopapilledema (PP) and to contrast the regional topography of the optic disc in PP and pseudotumor cerebri (PTC).
Three-dimensional optic disc images from 10 PP patients PP and 17 PTC patients were obtained using the Heidelberg Retinal Tomograph (HRT). Two conventional HRT parameters, volume above the reference plane and volume above the surface, were used to quantify global disc elevation. In addition, local topography was determined at 100 microm intervals along eight meridians at 100 to 1700 microm from the disc center. The global and local measures of disc topography in the two groups were compared statistically.
Significant between group differences were detected for both global measures. Regional analysis revealed vertical symmetry and horizontal asymmetry in PP and PTC as well as significant between group differences in peripapillary height.
CSL tomography can quantify disc elevation in both PP and PTC and may be useful for differentiating disc morphology in PP and PTC. The volume of the disc above the retinal surface is greater in PTC than in PP. However, most of the difference in elevation between the two groups occurs over the disc rim and peripapillary retina.
确定共焦扫描激光(CSL)断层扫描能否量化假性视乳头水肿(PP)患者的视盘地形图,并对比PP和假性脑瘤(PTC)患者视盘的局部地形图。
使用海德堡视网膜断层扫描仪(HRT)获取10例PP患者和17例PTC患者的三维视盘图像。采用两个传统的HRT参数,即参考平面上方的体积和表面上方的体积,来量化视盘整体抬高情况。此外,沿着距视盘中心100至1700微米的八条子午线,以100微米的间隔确定局部地形图。对两组视盘地形图的整体和局部测量值进行统计学比较。
两组在两种整体测量值上均检测到显著的组间差异。区域分析显示,PP和PTC存在垂直对称和水平不对称,且视乳头周围高度的组间差异显著。
CSL断层扫描可量化PP和PTC患者的视盘抬高情况,可能有助于区分PP和PTC患者的视盘形态。PTC患者视网膜表面上方视盘的体积大于PP患者。然而,两组之间抬高差异的大部分出现在视盘边缘和视乳头周围视网膜。