Ulmer Anja, Kötter Ina, Pfaff Andreas, Fierlbeck Gerhard
University Hospital Tuebingen, Tübingen, Germany.
J Am Acad Dermatol. 2002 Jan;46(1):123-7. doi: 10.1067/mjd.2001.118539.
We describe a 69-year-old patient with long-standing mixed connective tissue disease who suffered from severe skin eruptions that did not respond to various immunosuppressive regimens. Therapy with high-dose intravenous immunoglobulin was successful in controlling the patient's disease without major side effects. We think that this regimen-although expensive-might be an interesting therapeutic option in selected patients with mixed connective tissue disease that is refractory to other treatment modalities.
我们描述了一位69岁患有长期混合性结缔组织病的患者，该患者患有严重的皮肤疹，对各种免疫抑制方案均无反应。大剂量静脉注射免疫球蛋白治疗成功控制了该患者的病情，且无重大副作用。我们认为，尽管这种治疗方案费用昂贵，但对于某些对其他治疗方式无效的混合性结缔组织病患者而言，可能是一种值得关注的治疗选择。
