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[两种人工血浆中有机磷酸酯农药的分布:FSB - FSP]

[Distribution of organophosphate pesticides in two artificial plasmas: FSB-FSP].

作者信息

Fournier E, Sonnier M, Lecorsier A

出版信息

Eur J Toxicol Environ Hyg. 1975 Jul-Aug;8(4):205-11.

PMID:1175696
Abstract

Here is an attempt to establish that a close relation exists between the chemical formulae of organophosphates and their affinities for lipids, proteins and water. We carried out this study on two systems similar to human plasma. First, each component was sorted, then the organophosphates were detected and titrated by gas chromatography with flame photometry detector. Thiophosphates had a greater affinity for lipids than phosphates. Fixation of proteins was only observed on three hydrophilous organophosphates: phosphamidon, dichlorvos, ciodrin.

摘要

以下是一项旨在证实有机磷酸酯的化学式与其对脂质、蛋白质和水的亲和力之间存在密切关系的尝试。我们在两个类似于人体血浆的系统上进行了这项研究。首先,对每个成分进行分类,然后通过带有火焰光度检测器的气相色谱法检测并滴定有机磷酸酯。硫代磷酸酯对脂质的亲和力比对磷酸酯的更大。仅在三种亲水性有机磷酸酯上观察到了蛋白质的固定:磷胺、敌敌畏、氯碘磷。

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