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咪唑对α-黑素细胞刺激素所致房水闪光反应的促进作用。

Facilitation by imidazole of the aqueous flare response to alpha-melanocyte stimulating hormone.

作者信息

Bengtsson E, Krakau C E

出版信息

Experientia. 1975 Sep 15;31(9):1054-6. doi: 10.1007/BF02326956.

DOI:10.1007/BF02326956
PMID:1175745
Abstract

MSH, like traumata to the eye, cause a permeability disturbance in rabbits, with protein leakage into the aqueous. The MSH effect was enormously increased by instillation of imidazole or pilocarpine. The MSH effect seems to engage a different mechanism than the prostaglandin-dependent action of other agents.

摘要

促黑素细胞激素（MSH）与眼外伤一样，会导致兔子出现通透性障碍，蛋白质渗漏到房水中。通过滴注咪唑或毛果芸香碱，MSH的作用会大大增强。MSH的作用机制似乎与其他药物依赖前列腺素的作用机制不同。

相似文献

1
Facilitation by imidazole of the aqueous flare response to alpha-melanocyte stimulating hormone.咪唑对α-黑素细胞刺激素所致房水闪光反应的促进作用。
Experientia. 1975 Sep 15;31(9):1054-6. doi: 10.1007/BF02326956.
2
The aqueous flare inducing effect of prostaglandin and alpha-melanocyte stimulating hormone [proceedings].前列腺素和α-黑素细胞刺激素的房水闪光诱导效应[会议论文集]
Acta Ophthalmol Suppl. 1975(125):55-7. doi: 10.1111/j.1755-3768.1975.tb01242.x.
3
The effect of imidazole on the disruption of the blood-aqueous barrier in the rabbit eye.咪唑对兔眼血-房水屏障破坏的影响。
Invest Ophthalmol. 1976 Apr;15(4):315-20.
4
The effect of theophylline on the breakdown of the blood-aqueous barrier in the rabbit eye.茶碱对兔眼血-房水屏障破坏的影响。
Invest Ophthalmol Vis Sci. 1977 Jul;16(7):636-40.
5
Interaction of adrenergic agents with alpha-melanocyte-stimulating hormone and infrared irradiation of the iris in the rabbit eye.肾上腺素能药物与α-黑素细胞刺激素的相互作用以及兔眼虹膜的红外照射
Invest Ophthalmol Vis Sci. 1977 Mar;16(3):209-17.
6
Melanocyte-stimulating activity in serum and the aqueous flare response in rabbits.兔血清中的促黑素细胞活性及房水闪光反应
J Endocrinol. 1970 Feb;46(2):285-6. doi: 10.1677/joe.0.0460285.
7
The effect of timolol maleate on the disruption of the blood-aqueous barrier in the rabbit eye.马来酸噻吗洛尔对兔眼血-房水屏障破坏的影响。
Invest Ophthalmol Vis Sci. 1981 Jun;20(6):726-32.
8
The effect of experimental uveitis on the uptake of prostaglandin E1 in the rabbit iris-ciliary body.实验性葡萄膜炎对兔虹膜睫状体中前列腺素E1摄取的影响。
Acta Ophthalmol (Copenh). 1977 Aug;55(4):688-95. doi: 10.1111/j.1755-3768.1977.tb05667.x.
9
The effect of polyphloretin phosphate on the aqueous flare response to alpha-melanocyte stimulating hormone.
Acta Ophthalmol (Copenh). 1977 Dec;55(6):976-85. doi: 10.1111/j.1755-3768.1977.tb05679.x.
10
Effects of the melanocyte stimulating hormone and of an induced serum factor on eye permeability and serum level of free fatty acids in the rabbit.促黑素细胞激素及一种诱导血清因子对兔眼通透性和血清游离脂肪酸水平的影响。
Acta Endocrinol (Copenh). 1968 Nov;59(3):487-96. doi: 10.1530/acta.0.0590487.

本文引用的文献

1
QUANTITATIVE RELATIONS IN THE AQUEOUS FLARE RESPONSE INDUCED BY ALPHA-MELANOCYTE STIMULATING HORMONE IN THE RABBIT EYES.α-黑素细胞刺激素诱导兔眼房水闪光反应的定量关系
Acta Endocrinol (Copenh). 1965 May;49:166-76. doi: 10.1530/acta.0.0490166.
2
AQUEOUS FLOW DETERMINATION IN THE RABBIT BY MEANS OF A MINIMAL EYE TRAUMA.
Invest Ophthalmol. 1964 Apr;3:127-34.
3
Adenosine 3',5'-phosphate in biological materials. I. Purification and properties of cyclic 3',5'-nucleotide phosphodiesterase and use of this enzyme to characterize adenosine 3',5'-phosphate in human urine.生物材料中的3',5'-磷酸腺苷。I. 环3',5'-核苷酸磷酸二酯酶的纯化及性质，以及用该酶鉴定人尿中的3',5'-磷酸腺苷
J Biol Chem. 1962 Apr;237:1244-50.
4
Prostaglandin influences on intraocular pressure and pupil size.前列腺素对眼压和瞳孔大小的影响。
Am J Physiol. 1967 Feb;212(2):329-34. doi: 10.1152/ajplegacy.1967.212.2.329.
5
Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs.抑制前列腺素合成作为阿司匹林类药物的作用机制。
Nat New Biol. 1971 Jun 23;231(25):232-5. doi: 10.1038/newbio231232a0.
6
The effects of prostaglandins on the intraocular pressure of the rabbit.前列腺素对兔眼内压的影响。
Br J Pharmacol. 1969 Sep;37(1):158-67. doi: 10.1111/j.1476-5381.1969.tb09533.x.
7
Role of calcium and prostaglandin (PGE 1 ) in the MSH-induced activation of adenylate cyclase in Xenopus laevis.钙和前列腺素（PGE1）在非洲爪蟾促黑素（MSH）诱导的腺苷酸环化酶激活中的作用。
Biochem Biophys Res Commun. 1973 May 1;52(1):130-6. doi: 10.1016/0006-291x(73)90964-9.
8
Indomethacin blocks arachidonic acid-induced elevation of intraocular pressure.吲哚美辛可阻断花生四烯酸诱导的眼压升高。
Prostaglandins. 1973 Jan;3(1):7-16. doi: 10.1016/0090-6980(73)90133-0.
9
Aspirin prevents the disruption of the blood-aqueous barrier in the rabbit eye.阿司匹林可防止兔眼血-房水屏障的破坏。
Nature. 1972 Jul 21;238(5360):158-9. doi: 10.1038/238158a0.
10
Evidence for separate receptors for melanophore stimulating hormone and catecholamine regulation of cyclic AMP in the control of melanophore responses.在黑素细胞反应控制中，促黑素细胞激素和儿茶酚胺对环磷酸腺苷调节存在不同受体的证据。
Br J Pharmacol. 1970 May;39(1):160-6. doi: 10.1111/j.1476-5381.1970.tb09565.x.