Delgado F, Bolufer J M, Grau E, Domingo C, Serrano F, Gómez S
Service of General and Digestive Surgery, Dr. Peset University Hospital, Valencia, Spain.
Surg Laparosc Endosc Percutan Tech. 1999 Apr;9(2):91-8.
An observational prospective cohort study was made to evaluate the results of laparoscopic colorectal cancer resection, in terms of recurrence and patient survival. Fifty consecutive patients were analyzed, subjected to abdominoperineal amputations of the rectum (n = 10), anterior rectal resection (n = 13), rectosigmoidectomy (n = 18), and other colectomies (right, left, segmentary) (n = 9). Mean follow-up was 21 months (maximum, 42 months). The tumors corresponded to stage I (TNM classification of the International Union Against Cancer) in 6 cases, stage II in 17, stage III in 18, and stage IV in 9 cases. Survival in stages I-IV was 100, 92, 79, and 18%, respectively, with a disease-free survival rate of 100, 70, and 49% in stages I-III, respectively. Recurrence was pelvic in four cases, with multiple growths, peritoneal carcinomatosis, lung metastases, and implantation in the port scar in one case each. To conclude, survival after a maximum follow-up period of 42 months was found to be acceptable and similar to the percentages reported in the literature for open surgery.
开展了一项观察性前瞻性队列研究,以评估腹腔镜结直肠癌切除术在复发和患者生存方面的结果。对连续50例患者进行了分析,这些患者接受了直肠腹会阴联合切除术(n = 10)、直肠前切除术(n = 13)、直肠乙状结肠切除术(n = 18)和其他结肠切除术(右半结肠、左半结肠、节段性结肠切除术)(n = 9)。平均随访时间为21个月(最长42个月)。肿瘤在国际抗癌联盟TNM分类中,6例为I期,17例为II期,18例为III期,9例为IV期。I-IV期的生存率分别为100%、92%、79%和18%,I-III期的无病生存率分别为100%、70%和49%。4例复发发生在盆腔,1例出现多处肿瘤生长、腹膜癌转移、肺转移,1例种植于切口瘢痕处。总之,在最长42个月的随访期后,发现生存率是可接受的,且与文献报道的开放手术的百分比相似。