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腹腔镜结肠癌切除术:欧洲内镜外科学会(EAES)共识

Laparoscopic resection of colon Cancer: consensus of the European Association of Endoscopic Surgery (EAES).

作者信息

Veldkamp R, Gholghesaei M, Bonjer H J, Meijer D W, Buunen M, Jeekel J, Anderberg B, Cuesta M A, Cuschierl A, Fingerhut A, Fleshman J W, Guillou P J, Haglind E, Himpens J, Jacobi C A, Jakimowicz J J, Koeckerling F, Lacy A M, Lezoche E, Monson J R, Morino M, Neugebauer E, Wexner S D, Whelan R L

机构信息

Department of General Surgery, Erasmus MC, P. O. Box 2040, 3000, Rotterdam, CA, The Netherlands.

出版信息

Surg Endosc. 2004 Aug;18(8):1163-85. doi: 10.1007/s00464-003-8253-3. Epub 2004 Jun 23.

Abstract

BACKGROUND

The European Association of Endoscopic Surgery (EAES) initiated a consensus development conference on the laparoscopic resection of colon cancer during the annual congress in Lisbon, Portugal, in June 2002.

METHODS

A systematic review of the current literature was combined with the opinions, of experts in the field of colon cancer surgery to formulate evidence-based statements and recommendations on the laparoscopic resection of colon cancer.

RESULTS

Advanced age, obesity, and previous abdominal operations are not considered absolute contraindications for laparoscopic colon cancer surgery. The most common cause for conversion is the presence of bulky or invasive tumors. Laparoscopic operation takes longer to perform than the open counterpart, but the outcome is similar in terms of specimen size and pathological examination. Immediate postoperative morbidity and mortality are comparable for laparoscopic and open colonic cancer surgery. The laparoscopically operated patients had less postoperative pain, better-preserved pulmonary function, earlier restoration of gastrointestinal function, and an earlier discharge from the hospital. The postoperative stress response is lower after laparoscopic colectomy. The incidence of port site metastases is <1%. Survival after laparoscopic resection of colon cancer appears to be at least equal to survival after open resection. The costs of laparoscopic surgery for colon cancer are higher than those for open surgery.

CONCLUSION

Laparoscopic resection of colon cancer is a safe and feasible procedure that improves short-term outcome. Results regarding the long-term survival of patients enrolled in large multicenter trials will determine its role in general surgery.

摘要

背景

2002年6月,欧洲内镜外科学会(EAES)在葡萄牙里斯本召开的年度大会期间发起了一次关于腹腔镜结肠癌切除术的共识发展会议。

方法

对当前文献进行系统回顾,并结合结肠癌手术领域专家的意见,以制定关于腹腔镜结肠癌切除术的循证声明和建议。

结果

高龄、肥胖和既往腹部手术不被视为腹腔镜结肠癌手术的绝对禁忌证。最常见的中转开腹原因是存在体积较大或浸润性肿瘤。腹腔镜手术的操作时间比开腹手术长,但在标本大小和病理检查方面结果相似。腹腔镜和开腹结肠癌手术的术后即刻发病率和死亡率相当。接受腹腔镜手术的患者术后疼痛较轻、肺功能保留较好、胃肠功能恢复较早且出院较早。腹腔镜结肠切除术后的术后应激反应较低。切口部位转移的发生率<1%。腹腔镜结肠癌切除术后的生存率似乎至少与开腹切除术后的生存率相当。腹腔镜结肠癌手术的费用高于开腹手术。

结论

腹腔镜结肠癌切除术是一种安全可行的手术方法,可改善短期预后。大型多中心试验中患者的长期生存结果将决定其在普通外科中的作用。

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