Control of growth and development of the feto-placental unit.
作者信息
Han V K, Carter A M
机构信息
CIHR Group in Fetal and Neonatal Health and Development, Lawson Health Research Institute and Child Health Research Institute, University of Western Ontario, London, Canada.
出版信息
Curr Opin Pharmacol. 2001 Dec;1(6):632-40. doi: 10.1016/s1471-4892(01)00108-4.
Abstract
Classical gene targeting has identified many genes important for fetal and placental development. Null mutation of these genes may lead to fetal growth restriction, malformation or embryonic death. Growth restriction of epigenetic basis can predispose to adult-onset diseases. The mechanisms underlying this process, termed 'fetal programming', are beginning to be understood.
摘要
Zotero 插件