Zimmermann P R, Poli de Figueiredo C E, Fonseca N A
Hospital São Lucas, School of Medicine, Pontificia Universidade Católica do Rio Grande do Sul, Porto Alegre, RS, Brazil.
Clin Nephrol. 2001 Nov;56(5):387-90.
To measure the quality of life (QOL) of patients on RRT with regard to depression, anxiety, and adjustment to illness.
The study was conducted between 1996 and 1998 at a teaching hospital in Porto Alegre, Brazil. The study population included 125 patients (transplant n = 64, hemodialysis n = 42 and continuous ambulatory peritoneal dialysis [CAPD] n = 19).
The Beck Depression Inventory (BDI), the State-Trait Anxiety Inventory (STAI), and the Psychosocial Adjustment to Illness Scale (PAIS) were used for patient assessment. Results were analyzed using the Kruskall-Wallis, Mann-Whitney and ANOVA tests.
Depression scores were higher for hemodialysis patients compared with transplant patients (H = 15.22; p < 0.005). CAPD patients had intermediate scores (no statistical difference). As far as anxiety was concerned, no statistical difference was observed when the groups were compared. In terms of adjustment to illness, hemodialysis patients were significantly less well adjusted than transplant patients (H = 23.34; p < 0.001). Patients on CAPD had intermediate scores, with no significant difference compared with the other two groups.
The overall quality of life of transplant patients is higher than that of hemodialysis patients.
评估接受肾脏替代治疗（RRT）的患者在抑郁、焦虑及疾病适应方面的生活质量（QOL）。
该研究于1996年至1998年在巴西阿雷格里港的一家教学医院进行。研究对象包括125例患者（肾移植患者64例，血液透析患者42例，持续性非卧床腹膜透析[CAPD]患者19例）。
采用贝克抑郁量表（BDI）、状态-特质焦虑量表（STAI）及疾病心理社会适应量表（PAIS）对患者进行评估。结果采用克氏检验、曼-惠特尼检验和方差分析进行分析。
血液透析患者的抑郁得分高于肾移植患者（H = 15.22；p < 0.005）。CAPD患者得分居中（无统计学差异）。就焦虑而言，各组之间比较未观察到统计学差异。在疾病适应方面，血液透析患者的适应情况明显不如肾移植患者（H = 23.34；p < 0.001）。CAPD患者得分居中，与其他两组相比无显著差异。
肾移植患者的总体生活质量高于血液透析患者。
