Landesz M, van Rij G, Luyten G
University Hospital Rotterdam, Department of Ophthalmology, The Netherlands.
J Refract Surg. 2001 Nov-Dec;17(6):634-40. doi: 10.3928/1081-597X-20011101-01.
To evaluate the efficacy, safety, predictability, and stability of implanting a polymethylmethacrylate (PMMA) phakic intraocular lens (PIOL) (the Artisan myopia lens) to correct high myopia.
An Artisan myopia lens was implanted in 78 consecutive eyes of 49 patients with preoperative myopia that ranged from -6.25 to -28.00 D. Mean patient age was 42.4 years. Mean follow-up was 10.7 months and all patients were followed for at least 6 months; 45 eyes had follow-up of 12 months, and 10 eyes had 24 months. The desired outcome was emmetropia in all eyes except for those eyes with preoperative myopia greater then -23.00 D.
Fifty-three eyes (67.9%) had a postoperative refraction at the last follow-up examination within +/-1.00 D of emmetropia, and 39 eyes (50.0%) had a postoperative refraction +/- within 0.50 D of emmetropia. The postoperative refraction remained stable during the entire follow-up period. Mean spectacle-corrected visual acuity improved from 20/32 preoperatively to 20/25 postoperatively. Mean postoperative uncorrected visual acuity was 20/32. There was no significant change in endothelial cell density from baseline. We did not encounter major complications.
Implantation of the Artisan myopia lens to correct high myopia resulted in a stable and fairly predictable refractive outcome. A significant endothelial cell change was not detected.
评估植入聚甲基丙烯酸甲酯（PMMA）有晶状体眼人工晶状体（PIOL）（Artisan近视晶状体）矫正高度近视的有效性、安全性、可预测性和稳定性。
对49例术前近视度数在-6.25至-28.00 D之间的患者的78只眼连续植入Artisan近视晶状体。患者平均年龄为42.4岁。平均随访时间为10.7个月，所有患者至少随访6个月；45只眼随访12个月，10只眼随访24个月。除术前近视度数大于-23.00 D的眼外，所有眼的预期结果均为正视。
在最后一次随访检查时，53只眼（67.9%）的术后屈光度数在正视眼的±1.00 D范围内，39只眼（50.0%）的术后屈光度数在正视眼的±0.50 D范围内。在整个随访期间，术后屈光度数保持稳定。平均矫正视力从术前的20/32提高到术后的20/25。术后平均裸眼视力为20/32。内皮细胞密度与基线相比无显著变化。未出现重大并发症。
植入Artisan近视晶状体矫正高度近视可获得稳定且相当可预测的屈光结果。未检测到内皮细胞有明显变化。
