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[给予β,β'-二氯二乙硫醚后犬血液中的糖蛋白]

[Glycoproteins in the blood of dogs after administration of beta, beta'-dichlorodiethylsulphide].

作者信息

Hrusovský J

出版信息

Vet Med (Praha). 1979 Nov;24(11):699-703.

PMID:117600
Abstract

The protein spectrum of the dog blood serum was studied after the administration of beta,beta'-dichlorodiethylsulphide. Paper electrophoresis was used for this purpose. Fuchsin-positive substances were determined after previous oxidation with periodic acid, which made it possible to reveal that the glycoproteins detected in this way were represented in serum proteins mostly in the fraction of alpha 2 globulins. After beta, beta'-dichlorodiethylsulphide intoxication the values of these glycoproteins significantly increase. The rise is statistically significant 24 hours after administration (average rise by 141%) and within the time scope it reaches its maximum in the terminal stage (rise by 210%).

摘要

在给予β,β'-二氯二乙硫醚后,对犬血清的蛋白质谱进行了研究。为此采用了纸电泳法。在用高碘酸预先氧化后测定了品红阳性物质,这使得能够揭示以这种方式检测到的糖蛋白在血清蛋白中主要以α2球蛋白部分存在。在β,β'-二氯二乙硫醚中毒后,这些糖蛋白的值显著增加。给药后24小时升高具有统计学意义(平均升高141%),并且在该时间段内,在末期达到最大值(升高210%)。

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