Gawlik B M, Linsinger T, Kramer G N, Lamberty A, Schimmel H
European Commission, DG JRC, Institute for Reference Materials and Measurements, Geel, Belgium.
Fresenius J Anal Chem. 2001 Oct;371(4):565-9. doi: 10.1007/s002160101018.
The lack of suitable certified reference materials for the determination of organic pollutants in water has become a major problem within the framework of the new European water policy. This paper highlights approaches towards the production of certified reference materials and their drawbacks. On the basis of experience gained from proficiency-testing schemes, analytical practice, and reference material production a new concept for the production of liquid reference materials to be used in support of European legislation is presented and discussed briefly. The concept is based on a standard-addition approach and the simulation of effects interfering with the analytical process by use of individual matrix constituents or matrix-mimicking substances in combination with water-miscible solvents. The concept enables quantification of dissolved organic compounds in unknown water samples and evaluation of the analytical process with the help of a reconstituted sample. Open questions for further research are also outlined.
在新的欧洲水政策框架内，缺乏用于测定水中有机污染物的合适认证参考物质已成为一个主要问题。本文重点介绍了认证参考物质的生产方法及其缺点。基于能力验证计划、分析实践和参考物质生产所获得的经验，提出并简要讨论了一种用于支持欧洲立法的液体参考物质生产的新概念。该概念基于标准加入法，并通过使用单个基质成分或基质模拟物质与水溶性溶剂相结合来模拟干扰分析过程的影响。该概念能够对未知水样中的溶解有机化合物进行定量，并借助重构样品对分析过程进行评估。还概述了有待进一步研究的开放性问题。
