Piotrowski T, Nasierowski T
I Kliniki Psychiatrycznej AM w Warszawie.
Psychiatr Pol. 2001 Jul-Aug;35(4):593-603.
Excessive daytime sleepiness is a serious medical problem. It appears against patient will, when he performs normal day activities. It significantly disturbes daily functioning and may be a cause of a serious accidents. Approximately 5% of the general population suffers from excessive daytime sleepiness. The most common cause of daytime sleepiness is sleep deprivation. It is also a symptom of many disorders and may be an effect of taking many drugs, especially sedative ones. Investigation continued in the seventies by W. Dement and M. Carscadon resulted in preparation of MSLT which became the most widely used, objective method of the assessment of excessive sleepiness. It has been quickly used in diagnosis of narcolepsy, obstructive sleep apnea, idiopathic hypersomnia, periodic limb movements, circadian rhythms disorders, insomnia investigations, clinical assessment of many drugs. However equipment requirements are not that complicated, but investigator knowledge and experience are the limitations of the method. We described the protocol of the test including EEG procedures, patient preparation, interpretation of the results and normal values. Indications for MSLT in the diagnosis of sleep disorders were outlined with the special emphasis on narcolepsy.
日间过度嗜睡是一个严重的医学问题。它在患者进行日常活动时违背其意愿出现。它会严重干扰日常功能，并且可能是严重事故的一个原因。大约5%的普通人群患有日间过度嗜睡。日间嗜睡最常见的原因是睡眠剥夺。它也是许多疾病的一种症状，并且可能是服用许多药物的结果，尤其是镇静药物。20世纪70年代由W. 德门特和M. 卡斯卡顿持续进行的研究导致了多导睡眠图多次睡眠潜伏期试验（MSLT）的准备，该试验成为评估过度嗜睡最广泛使用的客观方法。它已迅速用于发作性睡病、阻塞性睡眠呼吸暂停、特发性嗜睡症、周期性肢体运动、昼夜节律紊乱、失眠研究以及许多药物的临床评估。然而，设备要求并非那么复杂，但研究者的知识和经验是该方法的局限性。我们描述了该测试的方案，包括脑电图程序、患者准备、结果解释和正常值。概述了MSLT在睡眠障碍诊断中的适应证，特别强调了发作性睡病。
