Palascak R, Gamé X, Milcent S, Camparo P, Berlizot P, Houlgatte A
Service d'Urologie, Hôpital d'Instruction des armées du Val-de-Grâce, Paris, France. vdg.urologie&@libertysurf.fr
Prog Urol. 2001 Sep;11(4):695-9.
The authors report two cases of papillomatous squamous carcinoma of the bladder unrelated to schistosomiasis. Both patients were treated by endoscopic resection. The staging assessment comprised thoraco-abdominopelvic computed tomography. A papillomatous squamous carcinoma of the bladder was detected in both cases: one was classified as pT2 G1 N0 M0 and the other as pT1 G1 N0 M0. Recurrence was rapidly observed, at the first follow-up cystoscopy. The tumour initially classified as pT1 subsequently underwent transformation to sarcomatoid carcinoma with peritoneal metastases. Papillomatous squamous carcinoma of the bladder, a rare squamous cell carcinoma, is a well differentiated tumour with an exclusively local and regional development. The prognosis is determined by the degree of tumour invasion, with a high local recurrence rate. The prognosis of invasive tumours is identical to that of conventional squamous cell carcinoma. Therapeutic management is poorly defined, but the only curative treatment appears to be radical cystectomy.
作者报告了两例与血吸虫病无关的膀胱乳头状鳞状细胞癌病例。两名患者均接受了内镜切除术。分期评估包括胸腹部盆腔计算机断层扫描。两例均检测到膀胱乳头状鳞状细胞癌：一例分类为pT2 G1 N0 M0，另一例为pT1 G1 N0 M0。在首次随访膀胱镜检查时很快观察到复发。最初分类为pT1的肿瘤随后转变为伴有腹膜转移的肉瘤样癌。膀胱乳头状鳞状细胞癌是一种罕见的鳞状细胞癌，是一种高分化肿瘤，仅局部和区域发展。预后取决于肿瘤浸润程度，局部复发率高。浸润性肿瘤的预后与传统鳞状细胞癌相同。治疗管理尚不明确，但唯一的治愈性治疗似乎是根治性膀胱切除术。
