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[短程控释药物治疗新诊断肺结核患者过程中的肺功能变化]

[Changes in lung function in patients with newly-diagnosed tuberculosis during treatment with short courses of controlled drug therapy].

作者信息

Nefedov V B, Popova L A

出版信息

Probl Tuberk. 2001(7):27-31.

PMID:11763558
Abstract

In 54 new cases of tuberculosis, VC, FVC, FEV1, FEV1/VC%, PEF, MEF25, MEF50, MEF75, PaO2, PaCO2 were measured before, during, and after a short-term intensive controlled chemotherapy. Lung function improved in 57.4% of patients and deteriorated in 22.2%. There was a combination of better and worse lung function in 7.4%. The direction of functional changes depended on the form of tuberculosis, the extent of a tuberculous process, the duration and efficiency of chemotherapy.

摘要

在54例新确诊的肺结核病例中,在短期强化控制化疗前、化疗期间及化疗后测量了肺活量(VC)、用力肺活量(FVC)、第1秒用力呼气容积(FEV1)、FEV1/VC%、呼气峰值流速(PEF)、最大呼气中期流速25%(MEF25)、最大呼气中期流速50%(MEF50)、最大呼气中期流速75%(MEF75)、动脉血氧分压(PaO2)、动脉血二氧化碳分压(PaCO2)。57.4%的患者肺功能改善,22.2%的患者肺功能恶化。7.4%的患者肺功能有改善也有恶化。功能变化的方向取决于肺结核的类型、结核病变的范围、化疗的持续时间和疗效。

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