João I, Marques P, Namora J, Aguas M J, Rosário L, Carvalho A, Carrageta M
Department of Medicine and Cardiology, Garcia de Orta Hospital, Almada.
Rev Port Cardiol. 2001 Sep;20(9):877-80.
The so-called nonpathogenic neisseriae are common inhabitants of the upper respiratory tract in humans and are not usually regarded as pathogens. Neisseria meningitidis on the contrary may cause severe disease. These organisms are an uncommon cause of infective endocarditis. The authors report a case of a 64 year-old male, type II diabetic, previously asymptomatic, admitted to hospital because of fever, aphasia and right hemi-paresis. A systolic murmur was heard at the cardiac apex, and three blood cultures were positive for Neisseria meningitidis. The echocardiogram showed a vegetation on the posterior leaflet of the mitral valve, allowing the diagnosis of meningococcal endocarditis. The patient's clinical condition improved on intravenous penicillin therapy, and regression of fever, disappearance of the neurological signs and of the mitral valve vegetation were observed.
所谓的非致病性奈瑟菌是人类上呼吸道的常见寄居菌，通常不被视为病原体。相反，脑膜炎奈瑟菌可能会引发严重疾病。这些微生物是感染性心内膜炎的罕见病因。作者报告了一例64岁男性病例，该患者患有II型糖尿病，此前无症状，因发热、失语和右侧偏瘫入院。在心尖部听到收缩期杂音，三次血培养结果显示脑膜炎奈瑟菌阳性。超声心动图显示二尖瓣后叶有赘生物，从而确诊为脑膜炎球菌性心内膜炎。患者经静脉注射青霉素治疗后临床状况改善，发热消退，神经症状和二尖瓣赘生物消失。
